RRecombinant Human Insulin-like Growth Factor (IGF-1)

- Description

       Insulin-like growth factor-1 (IGF-1), also known as growth factor C (Somatamedin C), belongs to the insulin-like growth factor family and is structurally homologous to proinsulin. IGF-1 is a mutagenic polypeptide growth factor that stimulates the proliferation and survival of various cells such as muscle, bone and cartilage in vitro. IGF-1 binds to IGF-1R, IGF-2R and insulin receptors and activates a variety of signaling pathways involved in cell proliferation, differentiation, survival, growth, apoptosis and regeneration.Recombinant human insulin-like growth factor (IGF-1) consists of 70 amino acids and is a biologically active protein for cell culture. 

       This product is a lyophilized powder prepared by recombinant yeast, separated and purified by multiple steps, and then sterilized by filtration through a 0.22 μm filters and freeze-dried.

- Properties

 - Application

It is widely used in cell culture to enhance cell proliferation, cell growth and cell differentiation.

- Recommended Method

      It is recommended to centrifuge the powder to the bottom of the tube before opening the lid, then dissolve it in sterilized deionized water to prepare a storage solution of 100 μg/ml. It can be stored stably for 2 weeks at 2 °C ~ 8 °C.When diluted to a lower concentration (not less than 10 μg/ml), 0.1% tissue culture grade BSA or HSA is required.If it is necessary to extend the storage time, it is recommended to freeze at -80℃or -20℃ rather than multigelation. This product should be determined by experiment to determine the optimum concentration according to each specific application.

- Stability

     Transportation stability: It is transported in an ice pack to keep it active. 

     Storage stability: stable to 12 months at -15~-20℃, stable to 4 weeks at 2~8℃.Prepared as a storage solution of 100μg/ml, stable storage at 2~8℃ for one week.

- Notice and Disclaimer  

  Avoid long time storage in high temperature environment.

  Avoid contamination during operation of this product.